Automatic diagnosis of the 12-lead ECG using a deep neural network.

Journal: Nature communications
Published Date:

Abstract

The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are great expectations on how it might improve clinical practice. Here we present a DNN model trained in a dataset with more than 2 million labeled exams analyzed by the Telehealth Network of Minas Gerais and collected under the scope of the CODE (Clinical Outcomes in Digital Electrocardiology) study. The DNN outperform cardiology resident medical doctors in recognizing 6 types of abnormalities in 12-lead ECG recordings, with F1 scores above 80% and specificity over 99%. These results indicate ECG analysis based on DNNs, previously studied in a single-lead setup, generalizes well to 12-lead exams, taking the technology closer to the standard clinical practice.

Authors

  • Antônio H Ribeiro
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. antonio-ribeiro@ufmg.br.
  • Manoel Horta Ribeiro
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Gabriela M M Paixão
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Derick M Oliveira
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Paulo R Gomes
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Jéssica A Canazart
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Milton P S Ferreira
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Carl R Andersson
    Uppsala University, Uppsala, Sweden.
  • Peter W Macfarlane
    University of Glasgow, Glasgow, Scotland.
  • Wagner Meira
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Thomas B Schön
    Division of Systems and Control, Department of Information Technology (T.B.S.), Uppsala University, Sweden.
  • Antonio Luiz P Ribeiro
    Hospital das Clínicas and Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - sala 533/Universidade Federal de Minas Gerais (UFMG), Belo Horizonte - MG, Brazil. Electronic address: tom@hc.ufmg.br.