Variability in Plus Disease Identified Using a Deep Learning-Based Retinopathy of Prematurity Severity Scale.

Journal: Ophthalmology. Retina
PMID:

Abstract

PURPOSE: Retinopathy of prematurity is a leading cause of childhood blindness worldwide, but clinical diagnosis is subjective, which leads to treatment differences. Our goal was to determine objective differences in the diagnosis of plus disease between clinicians using an automated retinopathy of prematurity (ROP) vascular severity score.

Authors

  • Rene Y Choi
    Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, Oregon, United States.
  • James M Brown
    Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, MGH/Harvard Medical School, Charlestown, MA, United States.
  • Jayashree Kalpathy-Cramer
    Department of Radiology, MGH/Harvard Medical School, Charlestown, Massachusetts.
  • R V Paul Chan
    Ophthalmology, Illinois Eye and Ear Infirmary, Chicago, IL, United States.
  • Susan Ostmo
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.
  • Michael F Chiang
    National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • J Peter Campbell
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.