Efficacy of Real-Time Computer-Aided Detection of Colorectal Neoplasia in a Randomized Trial.

Journal: Gastroenterology
Published Date: May 1, 2020

Abstract

BACKGROUND & AIMS: One-fourth of colorectal neoplasias are missed during screening colonoscopies; these can develop into colorectal cancer (CRC). Deep learning systems allow for real-time computer-aided detection (CADe) of polyps with high accuracy. We performed a multicenter, randomized trial to assess the safety and efficacy of a CADe system in detection of colorectal neoplasias during real-time colonoscopy.

Authors

  • Alessandro Repici
    Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.
  • Matteo Badalamenti
    Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089, Italy. Electronic address: badalamenti.matteo@gmail.com.
  • Roberta Maselli
    Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Loredana Correale
    Endoscopy Unit, Humanitas Clinical Center - IRCCS, Rozzano, Italy.
  • Franco Radaelli
    Gastroenterology Department, Valduce Hospital, Como, Italy.
  • Emanuele Rondonotti
    Gastroenterology Unit, Valduce Hospital, Como, Italy.
  • Elisa Ferrara
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Marco Spadaccini
    Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Asma Alkandari
    Thanyan Alghanim Center for Gastroenterology and Hepatology, Alamiri Hospital, Kuwait, Kuwait.
  • Alessandro Fugazza
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Andrea Anderloni
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Piera Alessia Galtieri
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Gaia Pellegatta
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Silvia Carrara
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Milena Di Leo
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Vincenzo Craviotto
    Endoscopy Unit, Istituto Clinico Humanitas, Rozzano, Italy.
  • Laura Lamonaca
    Department of Gastroenterology, Humanitas Research Hospital, Milano, Italy.
  • Roberto Lorenzetti
    Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy.
  • Alida Andrealli
    Gastroenterology Department, Valduce Hospital, Como, Italy.
  • Giulio Antonelli
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italy.
  • Michael Wallace
    Department of Medicine, Mayo Clinic, Director, Digestive Diseases Research Program, Editor in Chief Gastrointestinal Endoscopy, President, Florida Gastroenterology Society, Jacksonville, Florida, USA.
  • Prateek Sharma
    Department of Gastroenterology and Hepatology, Kansas City VA Medical Center, Kansas City, Kansas, USA.
  • Thomas Rösch
    Department for Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf.
  • Cesare Hassan
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italy.

Keywords

External Resources

Popular Topics
Recent Journals