Functional recovery in multiple sclerosis patients undergoing rehabilitation programs is associated with plasma levels of hemostasis inhibitors.

Journal: Multiple sclerosis and related disorders
Published Date: Sep 1, 2020

Abstract

BACKGROUND: Increasing evidence for contribution of hemostasis components in multiple sclerosis (MS) has been reported. Hemostasis protein inhibitors display key regulatory roles, extending to regulation of innate immune response and inflammation, and promotion of blood-brain barrier integrity. Whereas the effects on hemostasis of exercise and rehabilitation strategies have been extensively investigated, relationships between MS rehabilitation strategies and hemostasis have not been previously reported.

Authors

  • Nicole Ziliotto
    Department of Life Sciences and Biotechnology, University of Ferrara; School of Medicine and Surgery, University of Milano - Bicocca, Monza, Italy.
  • Nicola Lamberti
    Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
  • Fabio Manfredini
    Neuroscience and Rehabilitation Department, Ferrara University Hospital, Via Aldo Moro 8, 44124, Ferrara, Italy. fabio.manfredini@unife.it.
  • Sofia Straudi
    Neuroscience and Rehabilitation Department, Ferrara University Hospital, Ferrara, Italy s.straudi@ospfe.it.
  • Marcello Baroni
    Department of Life Sciences and Biotechnology, University of Ferrara.
  • Veronica Tisato
    Department of Morphology, Surgery and Experimental Medicine, Section of Anatomy and Histology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Matteo Carantoni
    Department of Morphology, Surgery and Experimental Medicine and LTTA Centre, University of Ferrara, Ferrara, Italy.
  • Paola Secchiero
    Department of Morphology, Surgery and Experimental Medicine, Section of Anatomy and Histology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Nino Basaglia
    Neuroscience and Rehabilitation Department, Ferrara University Hospital, Ferrara, Italy.
  • Giovanna Marchetti
    Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
  • Francesco Bernardi
    Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.

Keywords

External Resources

Popular Topics
Recent Journals