Semantic segmentation of cerebrospinal fluid and brain volume with a convolutional neural network in pediatric hydrocephalus-transfer learning from existing algorithms.

Journal: Acta neurochirurgica
PMID:

Abstract

BACKGROUND: For the segmentation of medical imaging data, a multitude of precise but very specific algorithms exist. In previous studies, we investigated the possibility of segmenting MRI data to determine cerebrospinal fluid and brain volume using a classical machine learning algorithm. It demonstrated good clinical usability and a very accurate correlation of the volumes to the single area determination in a reproducible axial layer. This study aims to investigate whether these established segmentation algorithms can be transferred to new, more generalizable deep learning algorithms employing an extended transfer learning procedure and whether medically meaningful segmentation is possible.

Authors

  • Florian Grimm
    Division of Functional and Restorative Neurosurgery, Department of Neurosurgery, Eberhard Karls University, Tuebingen; and.
  • Florian Edl
    Department of Neurosurgery, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tubingen, Germany.
  • Susanne R Kerscher
    Department of Neurosurgery, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tubingen, Germany.
  • Kay Nieselt
    Integrative Transcriptomics, Interfaculty Institute for Biomedical Informatics, University of Tübingen, Tubingen, Germany.
  • Isabel Gugel
    Department of Neurosurgery, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tubingen, Germany.
  • Martin U Schuhmann
    Department of Neurosurgery, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tubingen, Germany.