AIMC Topic: Cerebrospinal Fluid
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Sex-related differences and associated transcriptional signatures in the brain ventricular system and cerebrospinal fluid development in full-term neonates.
Biology of sex differences
May 25, 2025
BACKGROUND: The cerebrospinal fluid (CSF) is known to serve as a unique environment for neurodevelopment, with specific proteins secreted by epithelial cells of the choroid plexus (CP) playing crucial roles in cortical development and cell differenti...
Enhanced U-Net for Infant Brain MRI Segmentation: A (2+1)D Convolutional Approach.
Sensors (Basel, Switzerland)
Feb 28, 2025
BACKGROUND: Infant brain tissue segmentation from MRI data is a critical task in medical imaging, particularly challenging due to the evolving nature of tissue contrasts in the early months of life. The difficulty increases as gray matter (GM) and wh...
Multimodal multiview bilinear graph convolutional network for mild cognitive impairment diagnosis.
Biomedical physics & engineering express
Jan 22, 2025
Mild cognitive impairment (MCI) is a significant predictor of the early progression of Alzheimer's disease (AD) and can serve as an important indicator of disease progression. However, many existing methods focus mainly on the image when processing b...
Cerebrospinal fluid-induced stable and reproducible SERS sensing for various meningitis discrimination assisted with machine learning.
Biosensors & bioelectronics
Sep 10, 2024
Cerebrospinal fluid (CSF)-based pathogen or biochemical testing is the standard approach for clinical diagnosis of various meningitis. However, misdiagnosis and missed diagnosis always occur due to the shortages of unusual clinical manifestations and...
Super-Resolving and Denoising 4D flow MRI of Neurofluids Using Physics-Guided Neural Networks.
Annals of biomedical engineering
Sep 2, 2024
PURPOSE: To obtain high-resolution velocity fields of cerebrospinal fluid (CSF) and cerebral blood flow by applying a physics-guided neural network (div-mDCSRN-Flow) to 4D flow MRI.
Decoding pulsatile patterns of cerebrospinal fluid dynamics through enhancing interpretability in machine learning.
Scientific reports
Aug 1, 2024
Analyses of complex behaviors of Cerebrospinal Fluid (CSF) have become increasingly important in diseases diagnosis. The changes of the phase-contrast magnetic resonance imaging (PC-MRI) signal formed by the velocity of flowing CSF are represented as...
Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus.
Journal of neurosurgery
Oct 6, 2023
OBJECTIVE: Standard MRI protocols lack a quantitative sequence that can be used to evaluate shunt-treated patients with a history of hydrocephalus. The objective of this study was to investigate the use of phase-contrast MRI (PC-MRI), a quantitative ...
Aging-related volume changes in the brain and cerebrospinal fluid using artificial intelligence-automated segmentation.
European radiology
Apr 15, 2023
OBJECTIVES: To verify the reliability of the volumes automatically segmented using a new artificial intelligence (AI)-based application and evaluate changes in the brain and CSF volume with healthy aging.
Semantic segmentation of cerebrospinal fluid and brain volume with a convolutional neural network in pediatric hydrocephalus-transfer learning from existing algorithms.
Acta neurochirurgica
Jun 25, 2020
BACKGROUND: For the segmentation of medical imaging data, a multitude of precise but very specific algorithms exist. In previous studies, we investigated the possibility of segmenting MRI data to determine cerebrospinal fluid and brain volume using a...
Plasma and cerebrospinal fluid population pharmacokinetic modeling and simulation of meropenem after intravenous and intrathecal administration in postoperative neurosurgical patients.
Diagnostic microbiology and infectious disease
Aug 17, 2018
Combined intravenous and local intrathecal administration of meropenem in patients after craniotomy is widely used to treat intracranial infections. However, the optimal dosing regimen of meropenem has not been investigated, posing a risk to treatmen...
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