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Cerebrospinal Fluid

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[Flow cytometry increases the proportion of valuable samples in cerebrospinal fluid with normal cell count in malignant blood diseases].

Revista medica de Chile
BACKGROUND: The alteration of cerebrospinal fluid (CSF) in hematologic neoplasms is a poor prognostic marker. The characteristics of CSF are usually analyzed by flow cytometry or cytology. However, paucicellular CSF samples (≤5 cells/dL) can sometime...

Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus.

Journal of neurosurgery
OBJECTIVE: Standard MRI protocols lack a quantitative sequence that can be used to evaluate shunt-treated patients with a history of hydrocephalus. The objective of this study was to investigate the use of phase-contrast MRI (PC-MRI), a quantitative ...

Plasma and cerebrospinal fluid population pharmacokinetic modeling and simulation of meropenem after intravenous and intrathecal administration in postoperative neurosurgical patients.

Diagnostic microbiology and infectious disease
Combined intravenous and local intrathecal administration of meropenem in patients after craniotomy is widely used to treat intracranial infections. However, the optimal dosing regimen of meropenem has not been investigated, posing a risk to treatmen...

Semantic segmentation of cerebrospinal fluid and brain volume with a convolutional neural network in pediatric hydrocephalus-transfer learning from existing algorithms.

Acta neurochirurgica
BACKGROUND: For the segmentation of medical imaging data, a multitude of precise but very specific algorithms exist. In previous studies, we investigated the possibility of segmenting MRI data to determine cerebrospinal fluid and brain volume using a...

Aging-related volume changes in the brain and cerebrospinal fluid using artificial intelligence-automated segmentation.

European radiology
OBJECTIVES: To verify the reliability of the volumes automatically segmented using a new artificial intelligence (AI)-based application and evaluate changes in the brain and CSF volume with healthy aging.

Decoding pulsatile patterns of cerebrospinal fluid dynamics through enhancing interpretability in machine learning.

Scientific reports
Analyses of complex behaviors of Cerebrospinal Fluid (CSF) have become increasingly important in diseases diagnosis. The changes of the phase-contrast magnetic resonance imaging (PC-MRI) signal formed by the velocity of flowing CSF are represented as...

Cerebrospinal fluid-induced stable and reproducible SERS sensing for various meningitis discrimination assisted with machine learning.

Biosensors & bioelectronics
Cerebrospinal fluid (CSF)-based pathogen or biochemical testing is the standard approach for clinical diagnosis of various meningitis. However, misdiagnosis and missed diagnosis always occur due to the shortages of unusual clinical manifestations and...

Super-Resolving and Denoising 4D flow MRI of Neurofluids Using Physics-Guided Neural Networks.

Annals of biomedical engineering
PURPOSE: To obtain high-resolution velocity fields of cerebrospinal fluid (CSF) and cerebral blood flow by applying a physics-guided neural network (div-mDCSRN-Flow) to 4D flow MRI.

Multimodal multiview bilinear graph convolutional network for mild cognitive impairment diagnosis.

Biomedical physics & engineering express
Mild cognitive impairment (MCI) is a significant predictor of the early progression of Alzheimer's disease (AD) and can serve as an important indicator of disease progression. However, many existing methods focus mainly on the image when processing b...

Enhanced U-Net for Infant Brain MRI Segmentation: A (2+1)D Convolutional Approach.

Sensors (Basel, Switzerland)
BACKGROUND: Infant brain tissue segmentation from MRI data is a critical task in medical imaging, particularly challenging due to the evolving nature of tissue contrasts in the early months of life. The difficulty increases as gray matter (GM) and wh...