BIOINTMED: integrated biomedical knowledge base with ontologies and clinical trials.

Journal: Medical & biological engineering & computing
Published Date:

Abstract

Biomedical data are complex and heterogeneous. An ample reliable quantity of data is important for understanding and exploring the domain. The work aims to integrate biomedical data from various heterogeneous sources like dictionaries or corpus and amalgamate them into a uniform format for easier access by the end-user like biologist, pharmacist, and data scientist. The proposed integrated biomedical knowledge base, BIOINTMED, has 11,299, 12,981, 4428, 61,491, 48,663, and 13,146 unique entities for drugs, diseases, targets, genes, biomedical pathways, and adverse events, respectively. The uniform aggregated collection is also explored to study the interaction among these entity pairs. Finally, a complete statistical analysis of the consolidated biomedical entities is provided.

Authors

  • Ankita Saha
    Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, Kharagpur, India. ankitasaha@iitkgp.ac.in.
  • Jayanta Mukhopadhyay
    Department of Computer Science and Engineering, Indian Institute of Technology Kharagpur, Kharagpur, India.
  • Sudeshna Sarkar
    Department of Computer Science and Engineering, Indian Institute of Technology Kharagpur, Kharagpur, India.
  • Mahanandeeshwar Gattu
    Excelra Knowledge Solutions Pvt Ltd, Hyderabad, India.