Achalasia subtypes can be identified with functional luminal imaging probe (FLIP) panometry using a supervised machine learning process.

Journal: Neurogastroenterology and motility
PMID: 32608147

Abstract

BACKGROUND: Achalasia subtypes on high-resolution manometry (HRM) prognosticate treatment response and help direct management plan. We aimed to utilize parameters of distension-induced contractility and pressurization on functional luminal imaging probe (FLIP) panometry and machine learning to predict HRM achalasia subtypes.

Authors

  • Dustin A Carlson
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Wenjun Kou
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Katharine P Rooney
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Alexandra J Baumann
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Erica Donnan
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Joseph R Triggs
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Ezra N Teitelbaum
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Amy Holmstrom
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Eric Hungness
    Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Sajiv Sethi
    Department of Medicine, Division of Gastroenterology, University of South Florida, Tampa, FL, USA.
  • Peter J Kahrilas
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • John E Pandolfino
    Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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