Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study.

Journal: AJNR. American journal of neuroradiology
Published Date:

Abstract

BACKGROUND AND PURPOSE: Posterior fossa tumors are the most common pediatric brain tumors. MR imaging is key to tumor detection, diagnosis, and therapy guidance. We sought to develop an MR imaging-based deep learning model for posterior fossa tumor detection and tumor pathology classification.

Authors

  • J L Quon
    From the Departments of Neurosurgery (J.L.Q., G.A.G., M.S.B.E.).
  • W Bala
    Department of Radiology (W.B., J.S., M.P.L., K.W.Y.).
  • L C Chen
    Department of Urology (L.C.C.).
  • J Wright
    Department of Radiology (J.W.), Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.
  • L H Kim
    Stanford University School of Medicine (L.H.K., M.H., K.S.), Stanford, California.
  • M Han
    Stanford University School of Medicine (L.H.K., M.H., K.S.), Stanford, California.
  • K Shpanskaya
    Stanford University School of Medicine (L.H.K., M.H., K.S.), Stanford, California.
  • E H Lee
    Electrical Engineering (E.H.L.).
  • E Tong
    Radiology (E.T., M.I.).
  • M Iv
    Department of Radiology (K.W.Y., M.I.), Stanford University, Stanford, California.
  • J Seekins
    Department of Radiology (W.B., J.S., M.P.L., K.W.Y.).
  • M P Lungren
    Department of Radiology (W.B., J.S., M.P.L., K.W.Y.).
  • K R M Braun
    Departments of Clinical Radiology & Imaging Sciences (K.R.M.B., C.Y.H.), Riley Children's Hospital, Indiana University, Indianapolis, Indiana.
  • T Y Poussaint
    Departments of Radiology (T.Y.P.), Boston Children's Hospital, Boston, Massachusetts.
  • S Laughlin
    Departments of diagnostic Imaging (S.L.).
  • M D Taylor
    and Neurosurgery (M.D.T.).
  • R M Lober
    Department of Neurosurgery (R.M.L.), Dayton Children's Hospital, Wright State University Boonshoft School of Medicine, Dayton, Ohio.
  • H Vogel
    and Pathology (H.V.), Stanford University, Stanford, California.
  • P G Fisher
    Division of Child Neurology (P.G.F.), Lucile Packard Children's Hospital, Stanford University, Palo Alto, California.
  • G A Grant
    From the Departments of Neurosurgery (J.L.Q., G.A.G., M.S.B.E.).
  • V Ramaswamy
    and Haematology/Oncology (V.R.), The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • N A Vitanza
    Division of Pediatric Hematology/Oncology (N.A.V.), Department of Pediatrics, University of Washington, Seattle Children's Hospital, Seattle Washington.
  • C Y Ho
    Departments of Clinical Radiology & Imaging Sciences (K.R.M.B., C.Y.H.), Riley Children's Hospital, Indiana University, Indianapolis, Indiana.
  • M S B Edwards
    From the Departments of Neurosurgery (J.L.Q., G.A.G., M.S.B.E.).
  • S H Cheshier
    Departments of Neurosurgery (S.H.C.), University of Utah School of Medicine, Salt Lake City, Utah.
  • K W Yeom
    Department of Radiology (K.W.Y., M.I.), Stanford University, Stanford, California.