Importance of general adiposity, visceral adiposity and vital signs in predicting blood biomarkers using machine learning.

Journal: International journal of clinical practice
Published Date:

Abstract

INTRODUCTION: Blood biomarkers are measured for their ability to characterise physiological and disease states. Much is known about linear relations between blood biomarker concentrations and individual vital signs or adiposity indexes (eg, BMI). Comparatively little is known about non-linear relations with these easily accessible features, particularly when they are modelled in combination and can potentially interact with one another.

Authors

  • Weihong Zhou
    Health Management Centre, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
  • Yingjie Wang
    Cardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
  • Xiaoping Gu
    Department of Anaesthesiology, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
  • Zhong-Ping Feng
    Department of Physiology, University of Toronto, Toronto, ON, Canada.
  • Kang Lee
    Dr. Eric Jackman Institute of Child Study, University of Toronto, Toronto, M5R 2X2, Canada. kang.lee@utoronto.ca.
  • Yuzhu Peng
    Health Management Centre, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.
  • Andrew Barszczyk
    Department of Physiology, University of Toronto, Toronto, ON, Canada.