PSA-based machine learning model improves prostate cancer risk stratification in a screening population.

Journal: World journal of urology
Published Date:

Abstract

CONTEXT: The majority of prostate cancer diagnoses are facilitated by testing serum Prostate Specific Antigen (PSA) levels. Despite this, there are limitations to the diagnostic accuracy of PSA. Consideration of patient demographic factors and biochemical adjuncts to PSA may improve prostate cancer risk stratification. We aimed to develop a contemporary, accurate and cost-effective model based on objective measures to improve the accuracy of prostate cancer risk stratification.

Authors

  • Marlon Perera
    Faculty of Medicine, The University of Queensland, Brisbane, Australia.
  • Rohan Mirchandani
    Maxwell Plus, Brisbane, QLD, Australia.
  • Nathan Papa
    Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia.
  • Geoff Breemer
    Maxwell Plus, Brisbane, QLD, Australia.
  • Anna Effeindzourou
    Maxwell Plus, Brisbane, QLD, Australia.
  • Lewis Smith
    Maxwell Plus, Brisbane, QLD, Australia.
  • Peter Swindle
    Department of Urology, Mater Hospital, Brisbane, QLD, Australia.
  • Elliot Smith
    Maxwell Plus, Brisbane, QLD, Australia.