AIMC Topic: Prostate-Specific Antigen

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Combining multi-parametric MRI radiomics features with tumor abnormal protein to construct a machine learning-based predictive model for prostate cancer.

Scientific reports
This study aims to investigate the diagnostic value of integrating multi-parametric magnetic resonance imaging (mpMRI) radiomic features with tumor abnormal protein (TAP) and clinical characteristics for diagnosing prostate cancer. A cohort of 109 pa...

Effective reduction of unnecessary biopsies through a deep-learning-assisted aggressive prostate cancer detector.

Scientific reports
Despite being one of the most prevalent cancers, prostate cancer (PCa) shows a significantly high survival rate, provided there is timely detection and treatment. Currently, several screening and diagnostic tests are required to be carried out in ord...

Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.

European journal of radiology
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...

Prediction of prostate biopsy outcomes at different cut-offs of prostate-specific antigen using machine learning: a multicenter study.

Journal of the Egyptian National Cancer Institute
BACKGROUND: Machine learning (ML) is a significant area of artificial intelligence, which can improve the accuracy of predictive or diagnostic models for differentiating between prostate biopsy outcomes. This study aims to develop a novel decision-su...

Development of a deep learning system for predicting biochemical recurrence in prostate cancer.

BMC cancer
BACKGROUND: Biochemical recurrence (BCR) occurs in 20%-40% of men with prostate cancer (PCa) who undergo radical prostatectomy. Predicting which patients will experience BCR in advance helps in formulating more targeted prostatectomy procedures. Howe...

Integrating radiological and clinical data for clinically significant prostate cancer detection with machine learning techniques.

Scientific reports
In prostate cancer (PCa), risk calculators have been proposed, relying on clinical parameters and magnetic resonance imaging (MRI) enable early prediction of clinically significant cancer (CsPCa). The prostate imaging-reporting and data system (PI-RA...

Prediction of Prostate Cancer From Routine Laboratory Markers With Automated Machine Learning.

Journal of clinical laboratory analysis
BACKGROUND: In this study, we attempted to select the optimum cases for a prostate biopsy based on routine laboratory test results in addition to prostate-specific antigen (PSA) blood test using H2O automated machine learning (AutoML) software, which...

Using XBGoost, an interpretable machine learning model, for diagnosing prostate cancer in patients with PSA < 20 ng/ml based on the PSAMR indicator.

Scientific reports
To create a diagnostic tool before biopsy for patients with prostate-specific antigen (PSA) levels < 20 ng/ml to minimize prostate biopsy-related discomfort and risks. Data from 655 patients who underwent transperineal prostate biopsy at the First Af...

Multi-branch CNNFormer: a novel framework for predicting prostate cancer response to hormonal therapy.

Biomedical engineering online
PURPOSE: This study aims to accurately predict the effects of hormonal therapy on prostate cancer (PC) lesions by integrating multi-modality magnetic resonance imaging (MRI) and the clinical marker prostate-specific antigen (PSA). It addresses the li...