AIMC Topic: Prostate-Specific Antigen

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Performance of Retrieval-Augmented Generation Large Language Models in Guideline-Concordant Prostate-Specific Antigen Testing: Comparative Study With Junior Clinicians.

Journal of medical Internet research
BACKGROUND: Prostate-specific antigen (PSA) testing remains the cornerstone of early prostate cancer detection. Society guidelines for prostate cancer screening via PSA testing serve to standardize patient care and are often used by trainees, junior ...

Unveiling the role of harmonization on clinically significant prostate cancer detection using MRI.

Scientific reports
Accurate detection and classification of clinically significant prostate cancer remain critical challenges in medical imaging. Despite numerous studies focusing on feature extraction and classification, none have systematically assessed the impact of...

Prognostic Value of AI-Assisted Lesion Tracking on End-of-Treatment PSMA PET in mCRPC Patients Treated with Lu-PSMA: A Retrospective, Single-Center Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
This study aimed to explore the prognostic value of the artificial intelligence-assisted lesion tracking applied to prostate-specific membrane antigen (PSMA) PET in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with PS...

Deep Learning for Automated Measures of SUV and Molecular Tumor Volume in [Ga]PSMA-11 or [F]DCFPyL, [F]FDG, and [Lu]Lu-PSMA-617 Imaging with Global Threshold Regional Consensus Network.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Metastatic castration-resistant prostate cancer has a high rate of mortality with a limited number of effective treatments after hormone therapy. Radiopharmaceutical therapy with [Lu]Lu-prostate-specific membrane antigen-617 (LuPSMA) is one treatment...

Automating prostate volume acquisition using abdominal ultrasound scans for prostate-specific antigen density calculations.

Scientific reports
Proposed methods for prostate cancer screening are currently prohibitively expensive (due to the high costs of imaging equipment such as magnetic resonance imaging and traditional ultrasound systems), inadequate in their detection rates, require high...

Machine learning-based prediction of post-operative outcomes in robotic-assisted radical prostatectomy: a multi-variable analysis of 758 cases.

Journal of robotic surgery
Robotic-assisted radical prostatectomy (RARP) has become the gold standard treatment for localized prostate cancer. However, predicting post-operative outcomes remains challenging. This study aims to develop and validate predictive models for key out...

Artificial intelligence model for predicting early biochemical recurrence of prostate cancer after robotic-assisted radical prostatectomy.

Scientific reports
Prostate cancer remains a significant public health concern, with a substantial proportion of patients experiencing biochemical recurrence (BCR) after radical prostatectomy (RP). Traditional risk models, such as CAPRA-S, have demonstrated moderate pr...

Discovery of tumour indicating morphological changes in benign prostate biopsies through AI.

Scientific reports
Diagnostic needle biopsies that miss clinically significant prostate cancer (PCa) often sample benign tissue near hidden cancers. Such benign samples might still display subtle morphological signs of cancer elsewhere in the prostate. This study exami...

Multimodal data fusion with irregular PSA kinetics for automated prostate cancer grading.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Prostate cancer (PCa) detection and accurate grading remain critical challenges in medical diagnostics. While deep learning has shown promise in medical image analysis, existing computer-aided diagnosis approaches primarily focus on image recognition...

Combining multi-parametric MRI radiomics features with tumor abnormal protein to construct a machine learning-based predictive model for prostate cancer.

Scientific reports
This study aims to investigate the diagnostic value of integrating multi-parametric magnetic resonance imaging (mpMRI) radiomic features with tumor abnormal protein (TAP) and clinical characteristics for diagnosing prostate cancer. A cohort of 109 pa...