Recovery of reward function in problematic substance users using a combination of robotics, electrophysiology, and TMS.
Journal:
International journal of psychophysiology : official journal of the International Organization of Psychophysiology
PMID:
33068631
Abstract
BACKGROUND: Theoretical and empirical work suggest that addictive drugs potentiate dopaminergic reinforcement learning signals and disrupt the reward function of its neural targets, including the anterior midcingulate cortex (aMCC) and the basal ganglia. Here, we aim to use prefrontal 10-Hz TMS to enhance aMCC reward activity and reward learning by the basal ganglia in problematic substance users.