An artificial intelligence process of immunoassay for multiple biomarkers based on logic gates.
Journal:
The Analyst
PMID:
33237051
Abstract
We present a universal platform to synchronously analyze the possible existing state of two protein biomarkers. This platform is based on the integration of three logic gates: NAND, OR and NOT. These logic gates were constructed by the principle of immune recognition and fluorescence quenching between fluorescein labelled antibodies/antigens and antibody-conjugated graphene oxide (GO). An artificial intelligence (AI) protein analysis process was designed by us and accordingly a small program was written in JAVA. This protein analysis process with its JAVA code may be applied to give logic judgments on the possible existing state of two protein components. We expect that our fundamental research on multiple biomarker analysis can provide potential application in AI-assisted medical diagnosis with the interface for remote medical treatment.