AIMC Topic: Immunoassay

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Self-Powered Gravity Domino Microfluidics for Rapid At-Home Immunoassays with Artificial Intelligence.

ACS nano
At-home testing facilitates early screening and longitudinal monitoring of immune disorders, significantly enhancing patient engagement in personalized healthcare management. This convenient self-testing capability primarily stems from advancements i...

HepatoAI: Machine-Learning-Assisted Nano-enhanced Point-of-Care System for Personalized Precise Diagnosis of Hepatocellular Carcinoma.

Nano letters
Early diagnosis significantly improves survival rates for hepatocellular carcinoma (HCC), yet traditional methods face limitations, including specialized instruments/personnel and prolonged reporting cycles. While lateral flow immunoassay (LFA) offer...

Entropy-driven signal amplification integrated with machine learning in multiplex lateral flow immunoassay for sensitive Point-of-Care colon cancer diagnosis.

Journal of nanobiotechnology
Investigations on epithelial-mesenchymal transition (EMT) events occurring on circulating tumor cells (CTCs) are poised to significantly advance nanoliquid biopsy methodologies. This study presented a colorimetric multiplex lateral flow immunoassay s...

QDs fluorescent immunosensor based on magnetic separation coupled with machine learning for aflatoxin B1 detection in vegetable oils.

Food chemistry
Aflatoxin B1 (AFB1) is a common mycotoxin frequently found in vegetable oils. It poses a severe threat to public health, therefore there is a need for rapid and sensitive detection methods. In this study, a novel competitive immunofluorescent biosens...

"Sweet Nanosheet": An Antibody Mimic for Machine Learning-Assisted Ultra-Sensitive Immunochromatographic Assay for Pathogens.

Analytical chemistry
The bacterial surface is rich in diverse molecular features, and fully exploiting these natural recognition mechanisms provides innovative avenues for multimechanism detection of foodborne pathogens. Here, we developed a label-free, dual-modal LFIA p...

A Single-step Platinum Nanoparticle-Enhanced Lateral Flow Immunoassay Platform for Rapid Detection of Influenza A Virus.

ACS infectious diseases
Lateral flow immunoassays (LFIAs) are widely used point-of-care (POC) diagnostic tools, but their limited sensitivity can hinder reliable diagnoses. To address this limitation, we developed a novel POC diagnostic platform for the highly sensitive det...

AI-Enhanced Lateral Flow Assay Enables 3-Minute Quantitative Detection with Laboratory-Grade Accuracy.

Analytical chemistry
Lateral flow immunoassay (LFA) remains one of the most widely used point-of-care testing (POCT) platforms for disease diagnosis, food safety assessment, and environmental monitoring. However, traditional LFAs typically require up to 30 min and offer ...

A digital fluorescence immunoassay platform using a self-driven microfluidic cartridge with magnetic capture.

Biosensors & bioelectronics
Self-driven microfluidic devices have significantly advanced point-of-care testing (POCT) by enabling integration and automation of all the components required for biochemical analysis through capillary-driven fluid flow, eliminating the need for ext...

Hollow polydopamine for the enhanced ultrasensitive dual-modal immunochromatographic detection of Salmonella typhimurium in dairy products via machine learning.

Mikrochimica acta
Salmonella typhimurium (S. typhimurium) A dual-mode colorimetric/photothermal immunochromatographic strip (ICS) employing hollow polydopamine nanoparticles (h-PDA) is reported for the ultrasensitive detection of Salmonella typhimurium (S. typhimurium...

Collaborative Internal Cavity Effect and Interfacial Modulation Mechanism for Boosting Deep Learning-Powered Immunochromatographic Pathogen Detection.

Analytical chemistry
Nanoenabled immunochromatographic assay (ICA) emerges as a powerful tool for pathogen diagnosis, yet current nanotechnologies are still constrained by inadequate light-matter interaction efficiency, sluggish nanomaterial flow dynamics, and inefficien...