ARDD 2020: from aging mechanisms to interventions.

Journal: Aging
PMID: 33378272

Abstract

Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and advanced screening techniques, as well as a strong influence from the industry sector may lead to novel discoveries to treat age-related diseases. The present review summarizes presentations from the 7 Annual Aging Research and Drug Discovery (ARDD) meeting, held online on the 1 to 4 of September 2020. The meeting covered topics related to new methodologies to study aging, knowledge about basic mechanisms of longevity, latest interventional strategies to target the aging process as well as discussions about the impact of aging research on society and economy. More than 2000 participants and 65 speakers joined the meeting and we already look forward to an even larger meeting next year. Please mark your calendars for the 8 ARDD meeting that is scheduled for the 31 of August to 3 of September, 2021, at Columbia University, USA.

Authors

  • Garik V Mkrtchyan
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Kotb Abdelmohsen
    Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
  • Pénélope Andreux
    Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland.
  • Ieva Bagdonaite
    Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Nir Barzilai
    Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Søren Brunak
    NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
  • Filipe Cabreiro
    Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK.
  • Rafael de Cabo
    Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
  • Judith Campisi
    Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Ana Maria Cuervo
    Department of Developmental and Molecular Biology, Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Marco Demaria
    European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, The Netherlands.
  • Collin Y Ewald
    Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology Zürich, Switzerland.
  • Evandro Fei Fang
    Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478 Lørenskog, Norway.
  • Richard Faragher
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK.
  • Luigi Ferrucci
    Translational Gerontology Branch, Longitudinal Studies Section, National Institute on Aging, National Institutes of Health, MedStar Harbor Hospital, 3001 S. Hanover Street, Baltimore, MD, USA.
  • Adam Freund
    Calico Life Sciences, LLC, South San Francisco, CA 94080, USA.
  • Carlos G Silva-García
    Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
  • Anastasia Georgievskaya
    From Haut.AI OU.
  • Vadim N Gladyshev
    Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • David J Glass
    Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591, USA.
  • Vera Gorbunova
    Departments of Biology and Medicine, University of Rochester, Rochester, NY 14627, USA.
  • Aubrey de Grey
    SENS Research Foundation, Mountain View, CA 94041, USA.
  • Wei-Wu He
    Human Longevity Inc., San Diego, CA 92121, USA.
  • Jan Hoeijmakers
    Department of Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Eva Hoffmann
    DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Steve Horvath
    Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
  • Riekelt H Houtkooper
    Laboratory Genetic Metabolic Diseases, Amsterdam Gastroenterology, Endocrinology, and Metabolism, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • Majken K Jensen
    Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
  • Martin Borch Jensen
    Gordian Biotechnology, San Francisco, CA 94107, USA.
  • Alice Kane
    Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 94107, USA.
  • Moustapha Kassem
    Molecular Endocrinology Unit, Department of Endocrinology, University Hospital of Odense and University of Southern Denmark, Odense, Denmark.
  • Peter de Keizer
    Department of Molecular Cancer Research, Center for Molecular Medicine, Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Brian Kennedy
    Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Gerard Karsenty
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA.
  • Dudley W Lamming
    Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, USA.
  • Kai-Fu Lee
    Sinovation Ventures, Beijing, China.
  • Nanna MacAulay
    Department of Neuroscience, University of Copenhagen, Denmark.
  • Polina Mamoshina
    Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Emerging Technology Centers, Johns Hopkins University at Eastern, Baltimore, Maryland, USA.
  • Jim Mellon
    Juvenescence Limited, Douglas, Isle of Man, UK.
  • Marte Molenaars
    Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Alexey Moskalev
    George Mason University, Fairfax, VA, United States.
  • Andreas Mund
    Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • Laura Niedernhofer
    Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Brenna Osborne
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Heidi H Pak
    Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, USA.
  • Andrey Parkhitko
    University of Pittsburgh, Pittsburgh, PA 15260, USA.
  • Nuno Raimundo
    Institute of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany.
  • Thomas A Rando
    Department of Neurology and Neurological Sciences and Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Lene Juel Rasmussen
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Carolina Reis
    OneSkin Inc., San Francisco, CA 94107, USA.
  • Christian G Riedel
    Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden.
  • Anais Franco-Romero
    Department of Biomedical Sciences, University of Padova, Italy.
  • Björn Schumacher
    Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany.
  • David A Sinclair
    Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 94107, USA.
  • Yousin Suh
    Departments of Obstetrics and Gynecology, Genetics and Development, Columbia University, New York, NY 10027, USA.
  • Pam R Taub
    Division of Cardiovascular Medicine, University of California, San Diego, CA 92093, USA.
  • Debra Toiber
    Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
  • Jonas T Treebak
    Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Dario Riccardo Valenzano
    Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Eric Verdin
    Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Jan Vijg
    Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Sergey Young
    Longevity Vision Fund, New York, NY 10022, USA.
  • Lei Zhang
    Division of Gastroenterology, Union Hospital, Tongji Medical College Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Daniela Bakula
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Alex Zhavoronkov
    Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Emerging Technology Centers, Johns Hopkins University at Eastern, Baltimore, Maryland, USA.
  • Morten Scheibye-Knudsen
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark.

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