Deep learning for HGT insertion sites recognition.

Journal: BMC genomics
PMID: 33372605

Abstract

BACKGROUND: Horizontal Gene Transfer (HGT) refers to the sharing of genetic materials between distant species that are not in a parent-offspring relationship. The HGT insertion sites are important to understand the HGT mechanisms. Recent studies in main agents of HGT, such as transposon and plasmid, demonstrate that insertion sites usually hold specific sequence features. This motivates us to find a method to infer HGT insertion sites according to sequence features.

Authors

  • Chen Li
    School of Computer Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Jiaxing Chen
    School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
  • Shuai Cheng Li
    Department of Computer Science, City University of Hong Kong, Hong Kong, Hong Kong SAR, China.

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