Strategies to improve deep learning-based salivary gland segmentation.

Journal: Radiation oncology (London, England)
Published Date:

Abstract

BACKGROUND: Deep learning-based delineation of organs-at-risk for radiotherapy purposes has been investigated to reduce the time-intensiveness and inter-/intra-observer variability associated with manual delineation. We systematically evaluated ways to improve the performance and reliability of deep learning for organ-at-risk segmentation, with the salivary glands as the paradigm. Improving deep learning performance is clinically relevant with applications ranging from the initial contouring process, to on-line adaptive radiotherapy.

Authors

  • Ward van Rooij
    Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam, the Netherlands. Electronic address: w.vanrooij@vumc.nl.
  • Max Dahele
    Department of Radiotherapy, VU University Medical Center, Amsterdam, The Netherlands.
  • Hanne Nijhuis
    Department of Radiation Oncology, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam UMC, de Boelelaan 1117, Amsterdam, The Netherlands.
  • Berend J Slotman
    Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Wilko F Verbakel
    Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam, the Netherlands.