Using Machine Learning to Evaluate the Role of Microinflammation in Cardiovascular Events in Patients With Chronic Kidney Disease.

Journal: Frontiers in immunology
PMID: 35082785

Abstract

BACKGROUND: Lipid metabolism disorder, as one major complication in patients with chronic kidney disease (CKD), is tied to an increased risk for cardiovascular disease (CVD). Traditional lipid-lowering statins have been found to have limited benefit for the final CVD outcome of CKD patients. Therefore, the purpose of this study was to investigate the effect of microinflammation on CVD in statin-treated CKD patients.

Authors

  • Xiao Qi Liu
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Ting Ting Jiang
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Meng Ying Wang
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Wen Tao Liu
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Yang Huang
    School of Computer and Electronic Information, Nanjing Normal University, Nanjing 210023, China.
  • Yu Lin Huang
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Feng Yong Jin
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Qing Zhao
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Gui Hua Wang
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Xiong Zhong Ruan
    John Moorhead Research Laboratory, Department of Renal Medicine, University College London (UCL) Medical School, London, United Kingdom.
  • Bi Cheng Liu
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Kun Ling Ma
    Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.

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