Assessing the Adequacy of Hemodialysis Patients via the Graph-Based Takagi-Sugeno-Kang Fuzzy System.

Journal: Computational and mathematical methods in medicine
Published Date:

Abstract

Maintenance hemodialysis is the main method for the treatment of end-stage renal disease in China. The / value is the gold standard of hemodialysis adequacy. However, / requires repeated blood drawing and evaluation; it is hard to monitor dialysis adequacy frequently. In order to meet the need for repeated clinical assessments of dialysis adequacy, we want to find a noninvasive way to assess dialysis adequacy. Therefore, we collect some clinically relevant data and develop a machine learning- (ML-) based model to predict dialysis adequacy for clinical hemodialysis patients. We collect 250 patients, including gender, age, ultrafiltration (UF), predialysis body weight (preBW), postdialysis body weights (postBW), blood pressure (BP), heart rate (HR), and blood flow (BF). An efficient graph-based Takagi-Sugeno-Kang Fuzzy System (G-TSK-FS) model is proposed to predict the dialysis adequacy of hemodialysis patients. The root mean square error (RMSE) of our model is 0.1578. The proposed model can be used as a feasible method to predict dialysis adequacy, providing a new way for clinical practice. Our G-TSK-FS model could be used as a feasible method to predict dialysis adequacy, providing a new way for clinical practice.

Authors

  • Aiyan Du
    Hemodialysis Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, 214000 Wuxi, China.
  • Xiaofen Shi
    Nursing Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, 214000 Wuxi, China.
  • Xiaoyi Guo
    Hemodialysis Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, 214000 Wuxi, China.
  • Qixiao Pei
    Anesthesiology Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, 214000 Wuxi, China.
  • Yijie Ding
    School of Computer Science and Technology, Tianjin University, Tianjin 300350, China. wuxi_dyj@tju.edu.cn.
  • Wei Zhou
    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Qun Lu
    Internal Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, 214000 Wuxi, China.
  • Hua Shi
    School of Optoelectronic and Communication Engineering, Xiamen University of Technology, Xiamen 361024, China.