Deep learning system for lymph node quantification and metastatic cancer identification from whole-slide pathology images.

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Published Date: Jan 23, 2021

Abstract

BACKGROUND: Traditional diagnosis methods for lymph node metastases are labor-intensive and time-consuming. As a result, diagnostic systems based on deep learning (DL) algorithms have become a hot topic. However, current research lacks testing with sufficient data to verify performance. The aim of this study was to develop and test a deep learning system capable of identifying lymph node metastases.

Authors

  • Yajie Hu
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital and Institute, Beijing, China.
  • Feng Su
    Robotics Institute, Beihang University, Beijing, 100191, China.
  • Kun Dong
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing, 100142, China.
  • Xinyu Wang
    Department of Endocrinology, Institute of Translational Medicine, Health Science Center, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
  • Xinya Zhao
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing, 100142, China.
  • Yumeng Jiang
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing, 100142, China.
  • Jianming Li
    Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Jiafu Ji
    Gastrointestinal Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
  • Yu Sun
    Department of Neurology, China-Japan Friendship Hospital, Beijing, China.

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