Machine Learning-Based Prediction of Small Intracranial Aneurysm Rupture Status Using CTA-Derived Hemodynamics: A Multicenter Study.

Journal: AJNR. American journal of neuroradiology
Published Date: Mar 4, 2021

Abstract

BACKGROUND AND PURPOSE: Small intracranial aneurysms are being increasingly detected while the rupture risk is not well-understood. We aimed to develop rupture-risk models of small aneurysms by combining clinical, morphologic, and hemodynamic information based on machine learning techniques and to test the models in external validation datasets.

Authors

  • Z Shi
    From the Department of Medical Imaging (Z.S., B.H., Q.Q.N., G.M.L., L.J.Z.), Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
  • G Z Chen
    Department of Medical Imaging (G.Z.C.), Nanjing First Hospital, Nanjing, Jiangsu, China.
  • L Mao
    Deepwise AI Lab (L.M., X.L.L.), Beijing, China.
  • X L Li
    College of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
  • C S Zhou
    Department of Medical Imaging, Jinling Hospital, the First School of Clinical Medicine, Southern Medical University, Nanjing, 210002, China.
  • S Xia
    Department of Radiology (S.X.), Tianjin First Central Hospital, Tianjin, China.
  • Y X Zhang
    Laboratory of Image Science and Technology (Y.X.Z.), School of Computer Science and Engineering, Southeast University, Nanjing, China.
  • B Zhang
    Training Department, Third Military Medical University of Chinese PLA, Shapingba, Chongqing, China.
  • B Hu
    Department of Environmental Health, Harvard T.H. Chan School of Public Health, United States; Liberty Mutual Research Institute for Safety, United States. Electronic address: boyihu@hsph.harvard.edu.
  • G M Lu
    From the Department of Medical Imaging (Z.S., B.H., Q.Q.N., G.M.L., L.J.Z.), Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
  • L J Zhang
    From the Department of Medical Imaging (Z.S., B.H., Q.Q.N., G.M.L., L.J.Z.), Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China kevinzhlj@163.com.

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