Analysing wideband absorbance immittance in normal and ears with otitis media with effusion using machine learning.

Journal: Scientific reports
PMID:

Abstract

Wideband Absorbance Immittance (WAI) has been available for more than a decade, however its clinical use still faces the challenges of limited understanding and poor interpretation of WAI results. This study aimed to develop Machine Learning (ML) tools to identify the WAI absorbance characteristics across different frequency-pressure regions in the normal middle ear and ears with otitis media with effusion (OME) to enable diagnosis of middle ear conditions automatically. Data analysis included pre-processing of the WAI data, statistical analysis and classification model development, and key regions extraction from the 2D frequency-pressure WAI images. The experimental results show that ML tools appear to hold great potential for the automated diagnosis of middle ear diseases from WAI data. The identified key regions in the WAI provide guidance to practitioners to better understand and interpret WAI data and offer the prospect of quick and accurate diagnostic decisions.

Authors

  • Emad M Grais
    Centre for Speech and Language Therapy and Hearing Science, Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
  • Xiaoya Wang
    Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
  • Jie Wang
  • Fei Zhao
  • Wen Jiang
    School of Electronics and Information, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, P.R. China.
  • Yuexin Cai
    Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
  • Lifang Zhang
    Department of Neurology, Changzhi People's Hospital, Changzhi Medical College, Changzhi, China.
  • Qingwen Lin
    Department of Otolaryngology, Guangzhou Women and Children's Medical Centre, Guangzhou City, Guangdong Province, 510623, China.
  • Haidi Yang
    Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China; Institute of Hearing and Speech-Language Science, Sun Yat-sen University, China; Department of Hearing and Speech-Language Science, Xinhua College, Sun Yat-sen University, China. Electronic address: yanghd@mail.sysu.edu.cn.