Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial.

Journal: The lancet. Gastroenterology & hepatology
Published Date:

Abstract

BACKGROUND: White light endoscopy is a pivotal first-line tool for the detection of gastric neoplasms. However, gastric neoplasms can be missed during upper gastrointestinal endoscopy due to the subtle nature of these lesions and varying skill among endoscopists. Here, we aimed to evaluate the effect of an artificial intelligence (AI) system designed to detect focal lesions and diagnose gastric neoplasms on reducing the miss rate of gastric neoplasms in clinical practice.

Authors

  • Lianlian Wu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Renduo Shang
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Prateek Sharma
    Department of Gastroenterology and Hepatology, Kansas City VA Medical Center, Kansas City, Kansas, USA.
  • Wei Zhou
    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Jun Liu
    Department of Radiology, Second Xiangya Hospital, Changsha, Hunan, China.
  • Liwen Yao
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Zehua Dong
    Department of Internal Medicine, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, Hubei Province, China.
  • Jingping Yuan
    Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Zhi Zeng
    Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yuanjie Yu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Chunping He
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Qiutang Xiong
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yanxia Li
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yunchao Deng
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Zhuo Cao
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Chao Huang
    University of North Carolina, Chapel Hill, NC, USA.
  • Rui Zhou
    College of New Energy and Environment, Jilin University, Changchun 130021, China.
  • Hongyan Li
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Guiying Hu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yiyun Chen
    School of Resource and Environmental Sciences, Wuhan University, Wuhan 430079, China; State Key Laboratory of Soil and Sustainable Agriculture, Chinese Academy of Sciences, Nanjing 210008, China. Electronic address: chenyy@whu.edu.cn.
  • Yonggui Wang
    Hubei Key Laboratory of Critical Zone Evolution, School of Geography and Information Engineering, China University of Geosciences, Wuhan, China.
  • Xinqi He
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yijie Zhu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Honggang Yu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.