Automation of penicillin adverse drug reaction categorisation and risk stratification with machine learning natural language processing.

Journal: International journal of medical informatics
Published Date: Dec 1, 2021

Abstract

BACKGROUND: The penicillin adverse drug reaction (ADR) label is common in electronic health records (EHRs). However, there is significant misclassification between allergy and intolerance within the EHR and most patients can be delabelled after an immunologic assessment. Machine learning natural language processing may be able to assist with the categorisation and risk stratification of penicillin ADRs.

Authors

  • Joshua M Inglis
    Department of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, South Australia, Australia; Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia. Electronic address: joshua.m.inglis@gmail.com.
  • Stephen Bacchi
    Faculty of Health and Medical Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA 5000 Australia.
  • Alexander Troelnikov
    Clinical Immunology & Allergy, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
  • William Smith
    Alliance for Multispecialty Research, LLC, Knoxville, TN, USA.
  • Sepehr Shakib
    Department of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, South Australia, Australia; Discipline of Clinical Pharmacology, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.

Keywords

External Resources

Popular Topics
Recent Journals