Accurate segmentation for different types of lung nodules on CT images using improved U-Net convolutional network.

Journal: Medicine
Published Date:

Abstract

Since lung nodules on computed tomography images can have different shapes, contours, textures or locations and may be attached to neighboring blood vessels or pleural surfaces, accurate segmentation is still challenging. In this study, we propose an accurate segmentation method based on an improved U-Net convolutional network for different types of lung nodules on computed tomography images.The first phase is to segment lung parenchyma and correct the lung contour by applying α-hull algorithm. The second phase is to extract image pairs of patches containing lung nodules in the center and the corresponding ground truth and build an improved U-Net network with introduction of batch normalization.A large number of experiments manifest that segmentation performance of Dice loss has superior results than mean square error and Binary_crossentropy loss. The α-hull algorithm and batch normalization can improve the segmentation performance effectively. Our best result for Dice similar coefficient (0.8623) is also more competitive than other state-of-the-art segmentation algorithms.In order to segment different types of lung nodules accurately, we propose an improved U-Net network, which can improve the segmentation accuracy effectively. Moreover, this work also has practical value in helping radiologists segment lung nodules and diagnose lung cancer.

Authors

  • Xiaofang Zhang
    School of Computer Science and Technology, Soochow University, Suzhou 215006, People's Republic of China.
  • Xiaomin Liu
    State Grid Ningxia Electric Power, Eco-Tech Research Institute, Yinchuan, China.
  • Bin Zhang
    Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Jie Dong
    Department of Urology, Eastern Theater Command General Hospital, Nanjing,Jiangsu 210002, Chinia.
  • Shujun Zhao
    School of Physics and Microelectronics, Zhengzhou University, Zhengzhou, P.R. China.
  • Suxiao Li
    School of Physics and Microelectronics, Zhengzhou University, Zhengzhou, P.R. China.