Characterizing impact of positive lymph node number in endometrial cancer using machine-learning: A better prognostic indicator than FIGO staging?

Journal: Gynecologic oncology
Published Date:

Abstract

BACKGROUND: Number of involved lymph nodes (LNs) is a crucial stratification factor in staging of numerous disease sites, but has not been incorporated for endometrial cancer. We evaluated whether number of involved LNs provide improved prognostic value.

Authors

  • Colton Ladbury
    Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Richard Li
    Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Jay Shiao
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
  • Jason Liu
    Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America.
  • Mihaela Cristea
    Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Ernest Han
    Department of Gynecologic Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Thanh Dellinger
    Department of Gynecologic Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Stephen Lee
    Department of Gynecologic Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Edward Wang
    Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Christine Fisher
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
  • Yi-Jen Chen
    Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address: chenyj@vghtpe.gov.tw.
  • Arya Amini
    Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Tyler Robin
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
  • Scott Glaser
    Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA. Electronic address: sglaser@coh.org.