AIMC Topic: Neoplasm Staging
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Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis.
Scientific reports
Jul 1, 2025
Osteoarthritis (OA) has been implicated in the development and progression of early-stage endometrial cancer (EC), suggesting shared pathogenic factors between the two diseases. This study aimed to investigate the causal relationship between OA and E...
Machine learning model for predicting recurrence following intensity-modulated radiation therapy in nasopharyngeal carcinoma.
World journal of surgical oncology
Jun 18, 2025
BACKGROUND: Nasopharyngeal carcinoma (NPC) exhibits unique histopathological characteristics compared to other head and neck cancers. The prognosis of NPC patients after intensity-modulated radiation therapy (IMRT) has not been fully studied, and the...
Unsupervised learning-based quantitative analysis of CT intratumoral subregions predicts risk stratification of bladder cancer patients.
BMC medicine
Jun 2, 2025
BACKGROUND: Preoperative diagnosis of muscle invasion and American Joint Committee on Cancer (AJCC) stage plays a crucial role in guiding treatment strategies for bladder cancer (BCa). Utilizing quantitative analysis of tumor subregions via CT imagin...
AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.
Frontiers in endocrinology
May 27, 2025
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...
Integrative analysis of epigenetic and transcriptional interrelations identifies histotype-specific biomarkers in early-stage ovarian carcinoma.
Journal of ovarian research
May 19, 2025
BACKGROUND: Epithelial ovarian cancer (EOC) is a deadly and heterogenous disease comprising five major histotypes: clear cell carcinoma (CCC), endometrioid carcinoma (EC), low- and high-grade serous carcinoma (LGSC, HGSC), and mucinous carcinoma (MC)...
Tumor budding and poorly differentiated clusters as a biological continuum in colorectal cancer invasion and prognosis.
Scientific reports
May 15, 2025
Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent prognostic factors in colorectal cancer (CRC), yet the underlying biological mechanisms behind their role in CRC invasi...
Exploring the potential of machine learning in gastric cancer: prognostic biomarkers, subtyping, and stratification.
BMC cancer
Apr 30, 2025
BACKGROUND: Advancements in the management of gastric cancer (GC) and innovative therapeutic approaches highlight the significance of the role of biomarkers in GC prognosis. Machine-learning (ML)-based methods can be applied to identify the most impo...
Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.
American journal of otolaryngology
Apr 24, 2025
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...
A comparative analysis of three graph neural network models for predicting axillary lymph node metastasis in early-stage breast cancer.
Scientific reports
Apr 22, 2025
The presence of axillary lymph node metastasis (ALNM) in breast cancer patients is an important factor in deciding whether to have axillary surgery or pursue alternative treatments. Based on axillary ultrasound (US) and histopathologic data, three gr...
Updated perspectives on visceral pleural invasion in non-small cell lung cancer: A propensity score-matched analysis of the SEER database.
Current problems in cancer
Apr 18, 2025
BACKGROUND: Visceral pleural invasion (VPI), including PL1 (the tumor invades beyond the elastic layer) and PL2 (the tumor extends to the surface of the visceral pleura), plays a crucial role in staging Non-Small Cell Lung Cancer (NSCLC). However, th...
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