Identification of two robust subclasses of sepsis with both prognostic and therapeutic values based on machine learning analysis.

Journal: Frontiers in immunology
Published Date:

Abstract

BACKGROUND: Sepsis is a heterogeneous syndrome with high morbidity and mortality. Optimal and effective classifications are in urgent need and to be developed.

Authors

  • Wei Zhou
    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Chunyu Zhang
    Department of Neurosurgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
  • Zhongwei Zhuang
    Department of Neurosurgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.
  • Jing Zhang
    MOEMIL Laboratory, School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu, China.
  • Chunlong Zhong
    Department of Neurosurgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.