BACKGROUND: Abdominal aortic aneurysm (AAA) refers to a lasting enlargement of the abdominal aorta. Senescence, a major risk factor of AAA, demonstrate positive connection with both the formation and rupture of aneurysms. Therefore, investigating the...
The aging male : the official journal of the International Society for the Study of the Aging Male
Jan 14, 2026
BACKGROUND: Prostate cancer (PCa) is a leading cause of male cancer-related death globally. While the gut microbiota is linked to PCa, its genetic association remains unclear.
BACKGROUND: Adult-type diffuse glioma (ADG) is the most common primary malignant tumor of the central nervous system. Its highly invasive nature, marked heterogeneity, and resistance to therapy contribute to a high risk of recurrence and poor prognos...
UNLABELLED: Early identification of children at high risk for moderate-to-severe obstructive sleep apnea (OSA) is crucial for timely intervention, yet is often hindered by limited access to polysomnography (PSG). We aimed to develop an interpretable ...
Amino acid metabolism plays a critical role in tumor growth and immune regulation, yet its comprehensive function in breast cancer remains underexplored. We developed an amino acid metabolism-related gene signature (AAMRGS) to predict prognosis and t...
BACKGROUND: Periodontitis (PD) is a chronic, multifactorial inflammatory disorder characterized by the progressive destruction of periodontal tissues. Increasing evidence indicates that the dysregulation of hypoxia-related genes (HRGs) plays a pivota...
Chronic kidney disease (CKD) is a growing public health problem worldwide. CKD not only leads to renal function decline but also increases the risk of multiple complications, sarcopenia being particularly common and severe. At present, there is a lac...
BACKGROUND: Radiomics and artificial intelligence have shown strong predictive capabilities in urinary stone research, particularly concerning stone composition, characteristics, and treatment outcomes. However, the association of stone radiomics and...
OBJECTIVE: To develop, validate, and compare a Traditional Multivariable Logistic Regression model with a Machine Learning-based LASSO Regression Model for predicting significant renal function recovery in adult patients undergoing surgical repair fo...
Advanced cervical cancer (aCC) is associated with a poor prognosis. This study aimed to develop and validate a deep learning-based risk stratification model to predict overall survival in aCC patients using pre-treatment CT images. A total of 396 pat...
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