miRNAs expression pattern and machine learning models elucidate risk for gastric GIST.

Journal: Cancer biomarkers : section A of Disease markers
Published Date: Jan 1, 2022

Abstract

BACKGROUND: Gatrointestinal stromal tumors (GISTs) are the main mesenchymal tumors found in the gastrointestinal system. GISTs clinical phenotypes differ significantly and their molecular basis is not yet completely known. microRNAs (miRNAs) have been involved in carcinogenesis pathways by regulating gene expression at post-transcriptional level.

Authors

  • Ioannis K Stefanou
    1st Propaedeutic Department of Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • Nikolas Dovrolis
    Laboratory of Biology, Department of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
  • Maria Gazouli
    Department of Basic Medical Sciences, Laboratory of Biology, National and Kapodistrian University of Athens, Athens, Greece.
  • Dimitrios Theodorou
    1st Propaedeutic Department of Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • Georgios K Zografos
    1st Propaedeutic Department of Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • Konstantinos G Toutouzas
    1st Propaedeutic Department of Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

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