Metabonomics of d-glucaro-1,4-lactone in preventing diethylnitrosamine-induced liver cancer in rats.

Journal: Pharmaceutical biology
PMID:

Abstract

CONTEXT: d-Glucaro-1,4-lactone (1,4-GL) exists in many vegetables and fruits. Metabonomics has not been used to investigate the role of 1,4-GL in preventing liver cancer.

Authors

  • Wenlong Yang
    a Department of Infectious Diseases , the Second Affiliated Hospital of Nanchang University; School of Pharmaceutical Science, Nanchang University , Nanchang , PR China.
  • Guanlin Zhou
    a Department of Infectious Diseases , the Second Affiliated Hospital of Nanchang University; School of Pharmaceutical Science, Nanchang University , Nanchang , PR China.
  • Shubing Zou
    b Department of Hepatobiliary and Pancreatic Surgery , the Second Affiliated Hospital of Nanchang University , Nanchang , PR China.
  • Wentao Yang
    b Department of Hepatobiliary and Pancreatic Surgery , the Second Affiliated Hospital of Nanchang University , Nanchang , PR China.
  • Aihong Liu
    c Center of analysis and testing , Nanchang University , Nanchang , PR China.
  • Shuilin Sun
    a Department of Infectious Diseases , the Second Affiliated Hospital of Nanchang University; School of Pharmaceutical Science, Nanchang University , Nanchang , PR China.
  • Baogang Xie
    a Department of Infectious Diseases , the Second Affiliated Hospital of Nanchang University; School of Pharmaceutical Science, Nanchang University , Nanchang , PR China.