Development of a deep learning-based patient-specific target contour prediction model for markerless tumor positioning.

Journal: Medical physics
PMID:

Abstract

PURPOSE: For pancreatic cancer patients, image guided radiation therapy and real-time tumor tracking (RTTT) techniques can deliver radiation to the target accurately. Currently, for the radiation therapy machine with kV X-ray imaging systems, internal markers must be implemented to facilitate tumor tracking. The purpose of this study was to develop a markerless deep learning-based pancreatic tumor positioning procedure for real-time tumor tracking with a kV X-ray imaging system.

Authors

  • Dejun Zhou
    Department of Endoscopic Diagnosis and Therapy, National Clinical Research Center for Cancer, Key Laboratory of Molecular Cancer Epidemiology of Tianjin, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.
  • Mitsuhiro Nakamura
    Department of Radiation Oncology and Image-Applied Therapy, Kyoto University, Japan.
  • Nobutaka Mukumoto
    Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Michio Yoshimura
    Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan.
  • Takashi Mizowaki
    Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.