AIMC Topic: Radiotherapy, Intensity-Modulated
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Early prediction of proton therapy dose distributions and DVHs for hepatocellular carcinoma using contour-based CNN models from diagnostic CT and MRI.
Radiation oncology (London, England)
Aug 4, 2025
BACKGROUND: Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are typically assessed only afte...
Beam orientation optimization in IMRT using sparse mixed integer programming and non-convex fluence map optimization.
Physics in medicine and biology
Jul 4, 2025
Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is a complex, non-convex problem traditionally addressed with heuristic methods.This work demonstrates the potential improvement of the proposed BOO, providing a math...
Machine learning model for predicting recurrence following intensity-modulated radiation therapy in nasopharyngeal carcinoma.
World journal of surgical oncology
Jun 18, 2025
BACKGROUND: Nasopharyngeal carcinoma (NPC) exhibits unique histopathological characteristics compared to other head and neck cancers. The prognosis of NPC patients after intensity-modulated radiation therapy (IMRT) has not been fully studied, and the...
Evaluation of deliverable artificial intelligence-based automated volumetric arc radiation therapy planning for whole pelvic radiation in gynecologic cancer.
Scientific reports
Apr 30, 2025
This study aimed to develop a deep learning (DL)-based deliverable whole pelvic volumetric arc radiation therapy (VMAT) for patients with gynecologic cancer using a prototype DL-based automated planning support system, named RatoGuide, to evaluate it...
Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments.
Journal of applied clinical medical physics
Apr 23, 2025
Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra-hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter-fraction variabil...
Reinforcement learning-driven automated head and neck simultaneous integrated boost (SIB) radiation therapy: flexible treatment planning aligned with clinical preferences.
Physics in medicine and biology
Apr 22, 2025
Head-and-neck simultaneous integrated boost (SIB) treatment planning using intensity modulated radiation therapy is particularly challenging due to the proximity to organs-at-risk. Depending on the specific clinical conditions, different parotid-spar...
A machine learning toolkit assisted approach for IMRT fluence map optimization: feasibility and advantages.
Biomedical physics & engineering express
Apr 22, 2025
. Traditional machine learning (ML) and deep learning (DL) applications in treatment planning rely on complex model architectures and large, high-quality training datasets. However, they cannot fully replace the conventional optimization process. Thi...
Two-step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments.
Medical physics
Apr 18, 2025
BACKGROUND: In partial arc volumetric modulated arc therapy (VMAT) for treating breast cancer, setting up the limiting gantry positions of the treatment machine is a nontrivial yet repetitive and time-consuming task during planning. Templatized solut...
Evaluating the dosimetric and positioning accuracy of a deep learning based synthetic-CT model for liver radiotherapy treatment planning.
Biomedical physics & engineering express
Apr 11, 2025
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...
Portal dose image prediction using Monte Carlo generated transmission energy fluence maps of dynamic radiotherapy treatment plans: a deep learning approach.
Biomedical physics & engineering express
Apr 9, 2025
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...
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