AIMC Topic: Radiotherapy, Intensity-Modulated

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Integrating aperture shape controller and machine learning prediction to improve gamma passing rates in lattice radiotherapy.

Physics in medicine and biology
This study proposes a workflow integrating the aperture shape controller (ASC) in the Varian Eclipse system with a machine learning-based verification prediction model to improve gamma passing rates (GPRs) of LATTICE Radiotherapy (LRT) plans and redu...

New insights into automatic treatment planning for cancer radiotherapy using explainable artificial intelligence.

Physics in medicine and biology
This study aims to uncover the opaque decision-making process of an artificial intelligence (AI) agent for automatic treatment planning.We examined a previously developed AI agent based on the actor-critic with experience replay (ACER) network, which...

Dual-arc VMAT machine parameter optimization for localized prostate cancer using deep reinforcement learning.

Physics in medicine and biology
To develop and evaluate a deep reinforcement learning (RL) framework for rapid and automatic machine parameter optimization of volumetric modulated arc therapy (VMAT) treatment plans for localized prostate cancer.A multi-task policy network combining...

Integrating deep learning and multi-omics features in radiation pneumonitis prediction for lung cancer patients using PET/CT.

BMC medical imaging
BACKGROUND: To investigate the feasibility and accuracy of PET radiomics features, along with their combination with CT radiomics, dosiomics, and deep learning (DL) features, in predicting radiation pneumonitis (RP) in lung cancer patients treated wi...

Development and validation of a machine learning-based model for predicting radiation-induced hypothyroidism in nasopharyngeal carcinoma.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: This study aims to develop a robust and user-friendly prediction model for radiation-induced hypothyroidism (RIHT) in nasopharyngeal carcinoma (NPC) patients.

Research on error classification in gamma analysis on the basis of dosimetric feature engineering and deep learning.

Biomedical physics & engineering express
. Gamma analysis serves as a critical safety assurance tool in radiotherapy, yet its broader clinical implementation remains constrained by insufficient error cause determination. To address this limitation, this study proposes a gamma passing rate (...

Nasopharyngeal cancer adaptive radiotherapy with CBCT-derived synthetic CT: deep learning-based auto-segmentation precision and dose calculation consistency on a C-Arm linac.

Radiation oncology (London, England)
BACKGROUND: To evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images derived from cone-beam CT (CBC...

Criteria-calibration approaches to deep learning-based cervical cancer radiation treatment auto-planning.

Radiation oncology (London, England)
BACKGROUND: Knowledge-Based Planning (KBP) pipelines, which integrate machine learning-based models to predict dose distribution, have gained popularity in clinical radiation therapy. However, for patients with specific requirements, the trained mode...

Early prediction of proton therapy dose distributions and DVHs for hepatocellular carcinoma using contour-based CNN models from diagnostic CT and MRI.

Radiation oncology (London, England)
BACKGROUND: Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are typically assessed only afte...

Beam orientation optimization in IMRT using sparse mixed integer programming and non-convex fluence map optimization.

Physics in medicine and biology
Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is a complex, non-convex problem traditionally addressed with heuristic methods.This work demonstrates the potential improvement of the proposed BOO, providing a math...