AIMC Topic: Radiotherapy, Image-Guided

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Deep learning-based real-time detection of head and neck tumors during radiation therapy.

Physics in medicine and biology
Clinical drivers for real-time head and neck (H&N) tumor tracking during radiation therapy (RT) are accounting for motion caused by changes to the immobilization mask fit, and to reduce mask-related patient distress by replacing the masks with patien...

Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.

Physics in medicine and biology
To facilitate implementation of plan-of-the-day (POTD) selection for treating locally advanced cervical cancer (LACC), we developed a POTD assessment tool for CBCT-guided radiotherapy (RT). A female pelvis segmentation model (U-Seg3) is combined with...

Cone-beam computed tomography-based online adaptive radiotherapy of esophageal cancer in the neoadjuvant setting: Dosimetric analysis, toxicity and treatment response.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Chemoradiotherapy (CRT) followed by surgery is a treatment option for esophageal cancer (EC). However, concerns persist regarding cardiopulmonary toxicity and inconsistent daily target coverage due to anatomical changes. To ad...

Feasibility study of a general model for synthetic CT generation in MRI-guided extracranial radiotherapy.

Biomedical physics & engineering express
This study aims to investigate the feasibility of a single general model to synthesize CT images across body sites, thorax, abdomen, and pelvis, to support treatment planning for MRI-only radiotherapy. A total of 157 patients who received MRI-guided ...

Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

International journal of radiation oncology, biology, physics
BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online adaptive radiation therapy (oART). However, adaptation decisions rely on subjective image reviews by...

Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.

International journal of radiation oncology, biology, physics
PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some p...

A novel skeletal muscle quantitative method and deep learning-based sarcopenia diagnosis for cervical cancer patients treated with radiotherapy.

Medical physics
BACKGROUND: Sarcopenia is associated with decreased survival in cervical cancer patients treated with radiotherapy. Cone-beam computed tomography (CBCT) was widely used in image-guided radiotherapy. Sarcopenia is assessed by the skeletal muscle index...

Deep learning-based segmentation of head and neck organs at risk on CBCT images with dosimetric assessment for radiotherapy.

Physics in medicine and biology
Cone beam computed tomography (CBCT) has become an essential tool in head and neck cancer (HNC) radiotherapy (RT) treatment delivery. Automatic segmentation of the organs at risk (OARs) on CBCT can trigger and accelerate treatment replanning but is s...

Direct-to-Treatment Adaptive Radiation Therapy: Live Planning of Spine Metastases Using Novel Cone Beam Computed Tomography.

International journal of radiation oncology, biology, physics
PURPOSE: Cone beam computed tomography (CBCT)-based online adaptive radiation therapy is carried out using a synthetic CT (sCT) created through deformable registration between the patient-specific fan-beam CT, fan-beam computed tomography (FBCT), and...

Interstitial-guided automatic clinical tumor volume segmentation network for cervical cancer brachytherapy.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Automatic clinical tumor volume (CTV) delineation is pivotal to improving outcomes for interstitial brachytherapy cervical cancer. However, the prominent differences in gray values due to the interstitial needles bring great challenges on deep learni...