Estimation of the capillary level input function for dynamic contrast-enhanced MRI of the breast using a deep learning approach.

Journal: Magnetic resonance in medicine
Published Date:

Abstract

PURPOSE: To develop a deep learning approach to estimate the local capillary-level input function (CIF) for pharmacokinetic model analysis of DCE-MRI.

Authors

  • Jonghyun Bae
    Vilcek Institute of Graduate Biomedical Science, New York University School of Medicine, New York, New York, USA.
  • Zhengnan Huang
    Department of Radiology, New York University Grossman School of Medicine, 660 First Ave, 3rd Fl, New York, NY 10016.
  • Florian Knoll
    Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, New York, USA.
  • Krzysztof Geras
    Department of Radiology, NYU Langone Health / NYU Grossman School of Medicine, New York, New York.
  • Terlika Pandit Sood
    Center for Biomedical Imaging, Radiology, New York University School of Medicine, New York, New York, USA.
  • Li Feng
    Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
  • Laura Heacock
    Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
  • Linda Moy
    1 Department of Radiology, New York University School of Medicine, 160 E 34th St, New York, NY 10016.
  • Sungheon Gene Kim
    Department of Radiology, Weill Cornell Medical College, New York, NY. Electronic address: sgk4001@med.cornell.edu.