Virtifier: a deep learning-based identifier for viral sequences from metagenomes.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Feb 7, 2022
Abstract
MOTIVATION: Viruses, the most abundant biological entities on earth, are important components of microbial communities, and as major human pathogens, they are responsible for human mortality and morbidity. The identification of viral sequences from metagenomes is critical for viral analysis. As massive quantities of short sequences are generated by next-generation sequencing, most methods utilize discrete and sparse one-hot vectors to encode nucleotide sequences, which are usually ineffective in viral identification.