AIMC Topic: Microbiota

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Prediction of postoperative infection through early-stage salivary microbiota following kidney transplantation using machine learning techniques.

Renal failure
Kidney transplantation (KT) is an effective treatment for end-stage renal disease; however, the lifelong immunosuppressive regimen increases the risk of infection, presenting significant clinical, and economic challenges. Identifying predictive bioma...

Machine learning-based identification of wastewater treatment plant-specific microbial indicators using 16S rRNA gene sequencing.

Scientific reports
Effluent released from municipal wastewater treatment plants reflects the microbial communities responsible for degrading and removing contaminants within the plants. Monitoring this effluent offers essential insights into its environmental impacts, ...

Machine learning-based mapping of Acidobacteriota and Planctomycetota using 16 S rRNA gene metabarcoding data across soils in Russia.

Scientific reports
The soil microbiome plays a crucial role in maintaining healthy ecosystems and supporting sustainable agriculture. Studying its biogeographical structure and distribution is essential for understanding the rates and mechanisms of microbially mediated...

Responses of Microbial Community to Heterogeneous Dissolved Organic Nitrogen Constituents in the Hyporheic Zones of Treated Sewage-Dominated Rivers.

Microbial ecology
The hyporheic zone (HZ) of treated sewage-dominated rivers serves as a critical biogeochemical hotspot for dissolved organic nitrogen (DON) transformation, yet the mechanisms linking DON chemodiversity to microbial community dynamics remain poorly re...

Harnessing vaginal inflammation and microbiome: a machine learning model for predicting IVF success.

NPJ biofilms and microbiomes
Humans are the only species with a commensal Lactobacillus-dominant vaginal microbiota. Reproductive tract microbes have been linked to fertility outcomes, as has intrauterine inflammation, suggesting immune response may mediate adverse outcomes. In ...

Shotgun Metagenomics Identifies in a Cross-Sectional Setting Improved Plaque Microbiome Biomarkers for Peri-Implant Diseases.

Journal of clinical periodontology
AIM: This observational study aimed to verify and improve the predictive value of plaque microbiome of patients with dental implant for peri-implant diseases.

Visualizing fatigue mechanisms in non-communicable diseases: an integrative approach with multi-omics and machine learning.

BMC medical informatics and decision making
BACKGROUND: Fatigue is a prevalent and debilitating symptom of non-communicable diseases (NCDs); however, its biological basis are not well-defined. This exploratory study aimed to identify key biological drivers of fatigue by integrating metabolomic...

Single-tooth resolved, whole-mouth prediction of early childhood caries via spatiotemporal variations of plaque microbiota.

Cell host & microbe
Early childhood caries (ECC) exhibits tooth specificity, highlighting the need for single-tooth-level prevention. We profiled 2,504 dental plaque microbiota samples from 89 preschoolers across two cohorts, tracking compositional changes with imputed ...

TaxaCal: enhancing species-level profiling accuracy of 16S amplicon data.

BMC bioinformatics
BACKGROUND: 16S rRNA amplicon sequencing is a widely used method for microbiome composition analysis due to its cost-effectiveness and lower data requirements compared to metagenomic whole-genome sequencing (WGS). However, inherent limitations in 16S...

Distinguishing critical microbial community shifts from normal temporal variability in human and environmental ecosystems.

Scientific reports
Differentiating significant microbial community changes from normal fluctuations is vital for understanding microbial dynamics in human and environmental ecosystems. This knowledge could enable early warning systems to monitor critical changes affect...