A deep learning MRI approach outperforms other biomarkers of prodromal Alzheimer's disease.
Journal:
Alzheimer's research & therapy
Published Date:
Mar 29, 2022
Abstract
BACKGROUND: The three core pathologies of Alzheimer's disease (AD) are amyloid pathology, tau pathology, and neurodegeneration. Biomarkers exist for each. Neurodegeneration is often detected by neuroimaging, and we hypothesized that a voxel-based deep learning approach using structural MRI might outperform other neuroimaging methods.