The Xenopus phenotype ontology: bridging model organism phenotype data to human health and development.

Journal: BMC bioinformatics
PMID: 35317743

Abstract

BACKGROUND: Ontologies of precisely defined, controlled vocabularies are essential to curate the results of biological experiments such that the data are machine searchable, can be computationally analyzed, and are interoperable across the biomedical research continuum. There is also an increasing need for methods to interrelate phenotypic data easily and accurately from experiments in animal models with human development and disease.

Authors

  • Malcolm E Fisher
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Erik Segerdell
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Nicolas Matentzoglu
    School of Computer Science, University of Manchester, Oxford Road, Manchester, UK. nicolas.matentzoglu@manchester.ac.uk.
  • Mardi J Nenni
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Joshua D Fortriede
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Stanley Chu
    Department of Chemical and Biological Engineering, University of Colorado, Boulder, Colorado 80309, United States.
  • Troy J Pells
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • David Osumi-Sutherland
    European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK.
  • Praneet Chaturvedi
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Christina James-Zorn
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Nivitha Sundararaj
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Vaneet S Lotay
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Virgilio Ponferrada
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Dong Zhuo Wang
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Eugene Kim
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Sergei Agalakov
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Bradley I Arshinoff
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Kamran Karimi
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Peter D Vize
    Department of Biological Science, University of Calgary, Calgary, AB, Canada.
  • Aaron M Zorn
    Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. aaron.zorn@cchmc.org.

Keywords

External Resources

Popular Topics
Recent Journals