An interactive framework for the detection of ictal and interictal activities: Cross-species and stand-alone implementation.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: Despite advances on signal analysis and artificial intelligence, visual inspection is the gold standard in event detection on electroencephalographic recordings. This process requires much time of clinical experts on both annotating and training new experts for this same task. In scenarios where epilepsy is considered, the need for automatic tools is more prominent, as both seizures and interictal events can occur on hours- or days-long recordings. Although other solutions have already been proposed, most of them are not integrated on clinical and basic science environments due to their complexity and required specialization. Here we present a pipeline that arises from coordinated efforts between life-science researchers, clinicians and data scientists to develop an interactive and iterative workflow to train machine-learning tools for the automatic detection of electroencephalographic events in a variety of scenarios.

Authors

  • Guillermo M Besné
    Program of Neuroscience, Universidad de Navarra, CIMA, Avenida Pío XII, 55, 31008 Navarra, Pamplona, Spain.
  • Alejandro Horrillo-Maysonnial
    Clinical Neurophysiology Section, Clínica Universidad de Navarra, Pamplona, Spain.
  • María Jesús Nicolás
    Program of Neuroscience, Universidad de Navarra, CIMA, Avenida Pío XII, 55, 31008 Navarra, Pamplona, Spain.
  • Ferran Capell-Pascual
    Program of Neuroscience, Universidad de Navarra, CIMA, Avenida Pío XII, 55, 31008 Navarra, Pamplona, Spain.
  • Elena Urrestarazu
    Clinical Neurophysiology Section, Clínica Universidad de Navarra, Pamplona, Spain; IdiSNA, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
  • Julio Artieda
    Program of Neuroscience, Universidad de Navarra, CIMA, Avenida Pío XII, 55, 31008 Navarra, Pamplona, Spain; IdiSNA, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
  • Miguel Valencia
    Program of Neuroscience, Universidad de Navarra, CIMA, Avenida Pío XII, 55, 31008 Navarra, Pamplona, Spain; IdiSNA, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain; Institute of Data Science and Artificial Intelligence, Universidad de Navarra, Pamplona, Spain. Electronic address: mvustarroz@unav.es.