Relative Factors Analysis of Imatinib Trough Concentration in Chinese Patients with Gastrointestinal Stromal Tumor.

Journal: Chemotherapy
PMID:

Abstract

AIMS: Imatinib plasma trough levels (IM Cmin) have been reported to have a considerable clinical impact in patients with gastrointestinal stromal tumors (GISTs). We therefore have investigated the factors affecting IM plasma concentration in Chinese GIST patients.

Authors

  • Xingye Wu
    Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Juan Li
    Department of Hygienic Inspection, School of Public Health, Jilin University 1163 Xinmin Street Changchun 130021 Jilin China songxiuling@jlu.edu.cn li_juan@jlu.edu.cn jinmh@jlu.edu.cn +86 43185619441.
  • Yi Zhou
    Eye Center of Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Yun Mao
    Department of Imaging, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Shiqiao Luo
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Xuemei He
    Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li Wang
    College of Marine Electrical Engineering, Dalian Maritime University, Dalian, China.
  • Yifan Shen
    The Center for Clinical Molecular Medical Detection of Chongqing, Chongqing, China.
  • Hua Zhang
    School of Clinical Medicine, Hangzhou Medical College, Hangzhou, China.
  • Longwei Yang
    Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Jun Zhang
    First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.