Deep learning resting state functional magnetic resonance imaging lateralization of temporal lobe epilepsy.

Journal: Epilepsia
PMID: 35320587

Abstract

OBJECTIVE: Localization of focal epilepsy is critical for surgical treatment of refractory seizures. There remains a great need for noninvasive techniques to localize seizures for surgical decision-making. We investigate the use of deep learning using resting state functional magnetic resonance imaging (RS-fMRI) to identify the hemisphere of seizure onset in temporal lobe epilepsy (TLE) patients.

Authors

  • Patrick H Luckett
    Washington University in St. Louis, St. Louis, Missouri, USA.
  • Luigi Maccotta
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri, USA.
  • John J Lee
    Echocardiography Laboratory Mount Sinai Heart InstituteMount Sinai Medical Center Miami Beach FL.
  • Ki Yun Park
    Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
  • Nico U F Dosenbach
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri, USA.
  • Beau M Ances
    Department of Radiology, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Department of Neurology, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA.
  • Robert Edward Hogan
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri, USA.
  • Joshua S Shimony
    Department of Pediatrics, Washington University School of Medicine, Saint Louis, Missouri; Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri.
  • Eric C Leuthardt
    Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USA.

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