Development and Validation of a Deep Learning Model to Screen for Trisomy 21 During the First Trimester From Nuchal Ultrasonographic Images.

Journal: JAMA network open
PMID:

Abstract

IMPORTANCE: Accurate screening of trisomy 21 in the first trimester can provide an early opportunity for decision-making regarding reproductive choices.

Authors

  • Liwen Zhang
    National Engineering Laboratory of Big Data Analytics, Xi'an Jiaotong University, Xi'an 710049, China.
  • Di Dong
    The Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
  • Yongqing Sun
    Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Beijing Maternal and Child Health Care Hospital, China.
  • Chaoen Hu
    CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
  • Congxin Sun
    Department of Ultrasound, Shijiazhuang Obstetrics and Gynecology Hospital, Shijiazhuang, China.
  • Qingqing Wu
    Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Beijing Maternal and Child Health Care Hospital, China.
  • Jie Tian
    CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.