Clinical Validation of a Deep-Learning Segmentation Software in Head and Neck: An Early Analysis in a Developing Radiation Oncology Center.

Journal: International journal of environmental research and public health
Published Date: Jul 25, 2022

Abstract

BACKGROUND: Organs at risk (OARs) delineation is a crucial step of radiotherapy (RT) treatment planning workflow. Time-consuming and inter-observer variability are main issues in manual OAR delineation, mainly in the head and neck (H & N) district. Deep-learning based auto-segmentation is a promising strategy to improve OARs contouring in radiotherapy departments. A comparison of deep-learning-generated auto-contours (AC) with manual contours (MC) was performed by three expert radiation oncologists from a single center.

Authors

  • Andrea D'Aviero
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Alessia Re
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Francesco Catucci
    Fondazione Policlinico Universitario ''Agostino Gemelli'' IRCCS, Rome, Italy.
  • Danila Piccari
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Claudio Votta
    Fondazione Policlinico Universitario ''Agostino Gemelli'' IRCCS, Rome, Italy.
  • Domenico Piro
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Antonio Piras
    UO Radioterapia Oncologica, Villa Santa Teresa, 90011 Bagheria, Italy.
  • Carmela Di Dio
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Martina Iezzi
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Francesco Preziosi
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Sebastiano Menna
    Medical Physics, Mater Olbia Hospital, 07026 Sassari, Italy.
  • Flaviovincenzo Quaranta
    Medical Physics, Mater Olbia Hospital, 07026 Sassari, Italy.
  • Althea Boschetti
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Marco Marras
    Radiation Oncology, Mater Olbia Hospital, 07026 Olbia, Italy.
  • Francesco Miccichè
    UOC Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Roma, Italy.
  • Roberto Gallus
    Otolaryngology, Mater Olbia Hospital, 07026 Sassari, Italy.
  • Luca Indovina
    Fondazione Policlinico Universitario ''Agostino Gemelli'' IRCCS, Rome, Italy.
  • Francesco Bussu
    Otolaryngology, Azienda Ospedaliero Universitaria di Sassari, 07100 Sassari, Italy.
  • Vincenzo Valentini
    Agostino Gemelli University Polyclinic (IRCCS), Rome, Italy.
  • Davide Cusumano
    Polo Scienze Oncologiche ed Ematologiche, Fondazione Policlinico Universitario Agostino Gemelli, Largo A. Gemelli, 8, 00168 Rome, Italy.
  • Gian Carlo Mattiucci

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