Clinical and oncological outcomes of open partial nephrectomy versus robot assisted partial nephrectomy over 15 years.

Journal: Journal of robotic surgery
Published Date:

Abstract

Partial nephrectomy (PN) is the gold standard surgical treatment for localized kidney cancer. The objective of our study was to compare clinical and perioperative outcomes of open partial nephrectomy (OPN) and robotic-assisted partial nephrectomy (RAPN). We retrospectively collected all patients who underwent PN for kidney cancer between 2007 and 2019 at two French academic urology departments. Clinical and perioperative outcomes and complications were compared between the OPN group and the RAPN group. Recurrence-free survival (RFS) and overall survival (OS) were compared using the log-rank test. We included 405 patients. The maximum follow-up time was 13.6 years in the OPN group and 7.1 years in the RAPN group. The OPN group was associated with more blood loss and longer hospital stay (respectively, 287 ml vs. 62.1 ml; p < 0.001 and 8.54 days vs. 4.96 days; p < 0.001). Ischemia time was shorter in the OPN group (11.4 min vs. 16.9 min; p < 0.001). The rate of complications during hospitalization and after discharge from hospital was higher in the OPN group (respectively, n = 51 vs. 30; p = 0.031 and n = 31 vs. 14; p < 0.001). RFS and OS were similar in both groups. In our study, RAPN has better perioperative outcomes with shorter hospital stay and less blood loss but also fewer early and late complications. However, we did not find any difference in terms of RFS and OS.

Authors

  • Victor Audigé
    Department of Urology, University of Reims, Reims, France. audige.victor@gmail.com.
  • Adnan Baghli
    Department of Urology, University of Nancy, Nancy, France.
  • Jacques Hubert
    Service d'Urologie, CHRU Nancy, Vandoeeuvre-lès-Nancy, France.
  • Charles Mazeaud
    Department of Urology, CHRU Nancy Brabois University Hospital, Vandœuvre-lès-Nancy, France.
  • Stéphane Larré
    Department of Urology, University of Reims, Reims, France.
  • Benjamin Branchu
    Trenel Urology Center, Trenel Clinic, Saint Colombe, France.