Solid Attenuation Components Attention Deep Learning Model to Predict Micropapillary and Solid Patterns in Lung Adenocarcinomas on Computed Tomography.

Journal: Annals of surgical oncology
Published Date:

Abstract

BACKGROUND: High-grade adenocarcinoma subtypes (micropapillary and solid) treated with sublobar resection have an unfavorable prognosis compared with those treated with lobectomy. We investigated the potential of incorporating solid attenuation component masks with deep learning in the prediction of high-grade components to optimize surgical strategy preoperatively.

Authors

  • Li-Wei Chen
    Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
  • Shun-Mao Yang
    Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
  • Ching-Chia Chuang
    Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
  • Hao-Jen Wang
    Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
  • Yi-Chang Chen
    Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
  • Mong-Wei Lin
    Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
  • Min-Shu Hsieh
    Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
  • Mara B Antonoff
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: mbantonoff@mdanderson.org.
  • Yeun-Chung Chang
    Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
  • Carol C Wu
    University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tinsu Pan
    Department of Imaging Physics, M.D. Anderson Cancer Center, University of Texas, Houston, Texas, USA.
  • Chung-Ming Chen
    Institute of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.