Magnetic resonance imaging image analysis of the therapeutic effect and neuroprotective effect of deep brain stimulation in Parkinson's disease based on a deep learning algorithm.

Journal: International journal for numerical methods in biomedical engineering
PMID:

Abstract

In order to study the therapeutic neuroprotective effect of deep brain stimulation (DBS) in Parkinson's disease (PD), based on the deep learning algorithm, this study combines with magnetic resonance imaging (MRI) image analysis technology to study the clinical efficacy of DBS in the surgical treatment of PD and the neuroprotective and neurological recovery effects after surgery. Establish a deep learning algorithm model based on MRI image analysis technology, comparison of UPDRS motor status assessment and the improvement of daily life ability before and after DBS surgery, evaluate the accuracy rate and the detection speed of the model. The models constructed in this study have an accuracy rate of more than 90% in the PD detection test, and the detection speed of the algorithm model under the condition of big data is between 60 and 200 ms. DBS significantly improve a series of clinical symptoms in patients with PD. The deep learning algorithm model based on MRI image analysis technology in this paper has a certain effect. DBS operation can improve the symptoms of PD, and has the effect of neuroprotection and neurological recovery.

Authors

  • Jianzhong Zhang
    Wuxi Institute of Technology, Wuxi, Jiangsu 214121, China.
  • Chaoyang Zhou
    Department of Neurosurgery, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
  • Xiang Xiao
    Department of Neurosurgery, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
  • Weihua Chen
    Department of Imaging, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
  • Yi Jiang
    Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
  • Ronglan Zhu
    Department of Neurosurgery, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
  • Tao Xin
    Department of Neurosurgery, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.