Tumor Microenvironment, Radiology, and Artificial Intelligence: Should We Consider Tumor Periphery?

Journal: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Published Date: Aug 24, 2022

Abstract

OBJECTIVES: The tumor microenvironment (TME) consists of cellular and noncellular components which enable the tumor to interact with its surroundings and plays an important role in the tumor progression and how the immune system reacts to the malignancy. In the present study, we investigate the diagnostic potential of the TME in differentiating benign and malignant lesions using image quantification and machine learning.

Authors

  • Afshin Mohammadi
    Department of Radiology, Faculty of Medicine, Urmia University of Medical Science, Urmia, Iran. Electronic address: Afshin.mohdi@gmail.com.
  • Mohammad Mirza-Aghazadeh-Attari
    Medical Radiation Sciences Research Group, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Fariborz Faeghi
    Department of Radiology Technology, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hasan Homayoun
    Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Jamileh Abolghasemi
    Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
  • Thomas J Vogl
    Institute for Diagnostic and Interventional Radiology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Nathalie J Bureau
    Department of Radiology, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.
  • Mohsen Bakhshandeh
    Department of Radiology Technology, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Rajendra U Acharya
    Department of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore.
  • Ali Abbasian Ardakani
    Department of Radiology Technology, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Keywords

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