Development and validation of a deep learning signature for predicting lymph node metastasis in lung adenocarcinoma: comparison with radiomics signature and clinical-semantic model.

Journal: European radiology
Published Date:

Abstract

OBJECTIVE: To develop and validate a deep learning (DL) signature for predicting lymph node (LN) metastasis in patients with lung adenocarcinoma.

Authors

  • Xiaoling Ma
    Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
  • Liming Xia
    From the Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands (Q.T., E.H.M.P., D.P.S., A.d.R., H.J.L., R.J.v.d.G.); Department of Electrical Engineering, Fudan University, Shanghai, China (W.Y., Y.W.); Multidisciplinary Cardiovascular Research Centre & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, England (P.G., S.P.); Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (L.H., L.X.); and Departments of Cardiology (M.S.) and Radiology (J.T.), Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
  • Jun Chen
    Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Weijia Wan
    Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Qiaokou District, Wuhan, 430030, Hubei, China.
  • Wen Zhou
    Shanghai University, School of Computer Engineering and Science, Shanghai, China.